Name: YANG, Sze-Ming Mildred
Position: Professor, Food Science and Technology
Email: msyang@uic.edu.hk
Office:
T2-401-R37

Academic & Professional Qualifications

Academic Qualifications:

1979 Ph.D. Neurobiology, Department of Pharmacology, Washington University, St. Louis, Mo. USA
1974 M.A. Pharmacology, Columbia University, New York, N.Y. USA
1971 B.A. Chemistry, University of California, San Diego, USA
2011 IACM Conference on Modernization of Chinese Medicine & Health Products
2013 Certificate of Attendance, 2013 Symposium of Centre for Nutritional Studies, CUHK &, Food Safety & Technology Research, PolyU
Professional Activities:
1976- Member, American Association for the Advancement of Science
1986-1998 Member, Hong Kong Biochemical Society
1990- Member, International Society for the Study of Xenobiotics
1996 Organizing Committee, International Conference on the Remediation and Management of Degraded Lands, HKBU, Hong Kong
1997 Co-chairman, the Neuroscience 18th Annual Conference, Hong Kong Society of Neuroscience
1998 Local Organizational Committee, International Conference on Environmental Contamination, Toxicology and Health, Hong Kong
1997- Council member, Society of Chinese Toxicology - Molecular Biology and Biochemistry Specialist Group
1999 Research Fellow, Institute for the Advancement of Chinese Medicine, HKBU
2000- Member, Society of Toxicology, U.S.A.
Conference moderator, Genetically Modified Foods and the Consumer, Office of International Cooperation and Exchange, HKBU. Nov. 17, 2000.
2002 Invited reviewer for international journal, Journal of Clinical Pharmacology
2003 Delegate, People-to-People Ambassador Program for Toxicology
2005-2010 Editorial Board, Toxicology Mechanisms and Methods, Taylor & Francis
2009 Expert witness for K.C. Ho & Fong, Solicitors & Notaries on Chromium level in Cosmetics
Working experience:
2013- Director of General Education Office, BNU-HKBU UIC and Professor, Division of Science and Technology, Food Science and Technology Programme, BNU-HKBU UIC.
2012- Professor, Division of Science and Technology, Food Science and Technology Programme, BNU-HKBU UIC
2010-2013 Part-time lecturer for MSc Degree courses in Environmental and Public Health Risk Assessment, Department of Biology, Hong Kong Baptist University
2010-2013 Honorary lecturer for MSc Degree courses in Food Safety and Toxicology, School of Life Sciences, the University of Hong Kong
1995-2010 Associate Professor, Department of Biology, Hong Kong Baptist University
1993 Visiting Scientist, Institute of Ocean Science Chemistry Section. Sidney, B.C. Canada
1987-1995 Lecturer, Department of Biology, Hong Kong Baptist University
1986-1987 Research Associate, Department of Biochemistry, Chinese University of Hong Kong
1980-1985 Research Associate, Division of Neurosurgery, Medical College of Virginia, Richmond, Va. USA
1979-1980 Scientist, Sandoz Pharmaceutical Co., Basel, Switzerland
1970-1972 Research Assistant, Department of Pathology, University of California, San Diego, USA
Research Areas
  • Molecular mechanism of Chemicals (Cadmium, Organic compounds) toxicants
  • Free radical toxicity and antioxidants
  • Safety assessment of chemicals used in food production
  • Safety assessment of herbal medicine
Selected Publications

Peer-Reviewed articles (2004-2013)

  1. Yang M.S., Law, F.C.P., Wong R.N.S., Mak, N.K., Wei, X.Y. (2012) Interaction between oseltamivir and herbal medicines used for treating avian influenza. Hong Kong Medical Journal, 18 (Suppl. 5), 34-36.
  2. Hoi Hin Kwok, Wai Yee Ng, Mildred Sze Ming Yang, Nai Ki Mak, Ricky Ngok Shun Wong, Patrick Ying Kit Yue (2010). The ginsenoside protopanaxatriol protects endothelial cells from hydrogen peroxide-induced cell injury and cell death by modulating intracellular redox status. Free Radical Biology & Medicine 48, 437–445.
  3. Li Dong, Yang M.S., Lin T., Zheng W. and Qu, J.Y. (2009). Study of cadmium induced cytotoxicity using two-photon excitation endogenous fluorescence microscopy. J. Biomed. Optics. 14, 054028-1-8.
  4. Yang, M.S. and To, W.S. (2009). Toxicology of Benzo[a]pyrene. In: Polycyclic Aromatic Hydrocarbons: Pollution, Health Effects and Chemistry.” (ed. Pierre A. Haines and Milton D. Hendrickson), Nova Science Publishers, Inc. Chapter 10, pp. 249-262.
  5. Jun Wang, Tao Lin, Jiaping Lai, Zongwei Cai, M.S. Yang (2009). Analysis of adenosine phosphates in HepG-2 cell by a HPLC-ESI-MS system with porous graphitic carbon as stationary phase. J. Chrom. B 877, 2019-2024.
  6. Wang, F. Leung, A.O.W., Wu, S.C., Yang, M.S. and Wong M.H. (2009) Chemical and ecotoxicological analyses of sediments and elutriates of contaminated rivers due to e-waste recycling activities using a diverse battery of bioassays. Environ. Poll. 157, 2082-2090.
  7. Yang, M.S., Lin, T., D. Li and Qu, J.Y.(2008) Analysis of intracellular NADH level in the HepG2 cells and its relation with cellular energy level and cell death following acute cadmium exposure. In: Metal Ions. Vol. 10, 322-327. Collery P, Theophanides T, Maymard I, Collery P. (Eds.) John Libbey Eurotext, Paris.
  8. Wai Yee Ng and Mildred S Yang (2008). Effects of ginsenosides Re and Rg3 on intracellular redox state and cell proliferation in C6 glioma cells. Chinese Medicine 2008, 3:8
  9. Lin, T., Mak, N.K. and Yang, M.S. (2008). MAPK regulate p53-dependent cell death induced by Benzo[a]pyrene: involvement of p53 phosphorylation and acetylation. Toxicology 247, 145-153.
  10. Yang, M.S., Li, D, Lin, T., Zheng, J.J., Zheng, W. and Qu, J.Y. (2008) Increase in intracellular free/bound NAD[P]H as a cause of Cd induced oxidative stress in the HepG2 cells. Toxicology 247, 6-10.
  11. Lin T. and Yang, M. S. (2008) Benzo[a]pyrene induced necrosis in the HepG2 cells via PARP-1 activation and NAD+ depletion. Toxicology 245, 147-153.
  12. Lau, M.C., Chan, K.M., Leung, K.M.Y., Luan, T.G., Yang, M.S. and Qiu, J.W. (2007) Acute and chronic toxicity of tributyltin to various life stages of the marine polychaete Hydroides elegans. Chemosphere 69, 135-144.
  13. Yang M.S., Yu, L.C. and Pat S. W. (2007) Manipulation of energy and redox state in the C6 glioma cells by buthionine sulfoxamine and N-acetylcysteine and the effect on cell survival to Cd toxicity. Cellular and Mol. Biology, 53, 56-61.
  14. Lin, T. and Yang, M.S. (2007) Benzo[a]pyrene-induced elevation of GSH level protects against oxidative stress and enhances xenobiotic detoxification in human HepG2 cells. Toxicology, 235, 1-10.
  15. Yang, M.S., Chan H. W. and Yu, L.C. (2006). Gutathione peroxidase and glutathione reductase activities are partially responsible for determining the susceptibility of cells to oxidative stress. Toxicology 226, 126-139.
  16. Yang , M. S. , W. K.F. Tse, L. C. Yu, K.M. Li, Mak, N.K. and R. C. Gupta (2005). Energy and redox states in the C6 glioma cells following acute exposure to Zn, Se+4 and Se+6 and the correlation with apoptosis. Toxicol. Mech. Methods. 15, 29-32.
  17. Yang, M.S. Yu, L.C. and Gupta, R.C. (2005). Analysis of multiple metabolomics subsets in vitro: Methodological considerations. Toxicol. Mech. Methods 15, 29-32
  18. Cai Zongwei, Qian Tianxiu, and Yang, Mildred S.M. (2004). Ion-pairing liquid chromatography coupled with mass spectrometry for the simultaneous determination of nucleosides and nucleotides. Chinese J. Chromatography. 22, 358-360.
  19. Yang, M.S. Yu, L.C. and Gupta, R.C. (2004). Analysis of changes in energy and redox states in HepG2 hepatoma and C6 glioma cells upon exposure to Cd. Toxicology 201, 105-113.
Courses Taught at UIC
  • Microbiology
  • Food Microbiology and Toxicology
  • Quality Assurance and Food Safety
  • Food Science Laboratory
  • Introduction to Psychology
  • Science of Well Being